Novartis buying AveXis for $8.7 billion to strengthen gene therapy capabilities

first_imgPharma About the Author Reprints [email protected] Adam Feuerstein GET STARTED By Adam Feuerstein April 9, 2018 Reprints @adamfeuerstein Log In | Learn More Tags biotechpharmaceuticals Novartis buying AveXis for $8.7 billion to strengthen gene therapy capabilities Unlock this article by subscribing to STAT+ and enjoy your first 30 days free! GET STARTED Senior Writer, Biotech Adam is STAT’s national biotech columnist, reporting on the intersection of biotech and Wall Street. He’s also a co-host of “The Readout LOUD” podcast. Novartis is acquiring AveXis for $8.7 billion to strengthen its gene therapy unit, adding a promising but still experimental treatment targeting a fatal childhood disease.AveXis, a small biotech based in a north Chicago suburb, is being purchased for $218 per share, or an 88 percent premium to Friday’s closing stock price, Novartis said. Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr. What’s included? What is it? STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.last_img read more

MSMES to Benefit from $439 Million Govt Allocation to Productive Sector

first_imgAdvertisements FacebookTwitterWhatsAppEmail Micro, Small and Medium-Sized Enterprises(MSMEs) are to benefit from some $439 million, which the Government has earmarked for fiscal year 2013/14, to facilitate growth and development in the productive sector.Minister of Industry, Investment and Commerce, Hon. Anthony Hylton, said that 57 per cent of the funds, allocated through the Development Bank of Jamaica (DBJ), are slated for the Credit Enhancement Fund, through which businesses can access loan support.The Minister was addressing a forum on: ‘The IMF Agreement- Implications for Small Business,’ hosted by the Jamaica Business Development Corporation (JBDC) and the University of the West Indies (UWI) Business Centre on April 11, at the Mona School of Business and Management (MSBM). RelatedMSMES to Benefit from $439 Million Govt Allocation to Productive Sector RelatedMSMES to Benefit from $439 Million Govt Allocation to Productive Sectorcenter_img RelatedMSMES to Benefit from $439 Million Govt Allocation to Productive Sector MSMES to Benefit from $439 Million Govt Allocation to Productive Sector CommerceApril 13, 2013last_img read more

Show Jumping Returns to St. Lazare

first_imgThe 37th annual Pépinière and St. Lazare Horse Shows will be held May 18-22 and May 25-29 in St. Lazare, QC, with a record number of participants. Course designers for this year are Sven Loewe of North Carolina and Montreal’s own Olympic Silver Medalist, Michel Vaillancourt, who will be setting the tracks in the grass grand prix field.  One of the main attractions for riders to compete in St. Lazare is its rare natural grass footing, heralded as one of the best grass grand prix arenas in Canada. SIGN UP The two-week competition concludes on Sunday, May 29, with the popular Val Wagner Memorial Speed Derby, and a $5,000 Jump Canada Hunter Classic.  The future of show jumping sport will also be showcased during the Jump Canada Young Horse Development Series.  The Young Horse competition at the Concours Hippique de St. Lazare will be presented by Merial. Horse Sport Enews The second week of show jumping competition brings the Concours Hippique de St. Lazare.  Friday, May 28, will showcase the stars of the future with the Jump Canada Emerging Rider competition, presented by Agritex, and a Jump Canada Talent Squad Qualifier, Presented by Omega Alpha.  The feature event, the $25,000 Eastwood Equine Grand Prix, which also acts as a Jump Canada Cup qualifier, will take place on Saturday, May 28. “Our job is made much easier due to the pleasant setting, drainage and natural footing that the venue possesses,” said Mike Lawrence, President of Competition Eastwood Equine which manages the Pépinière and St. Lazare Horse Shows.  “Showing on grass is a rare opportunity in the sport today.  We are also privileged to be surrounded by a wonderful equestrian-friendly community in St. Lazare with excellent restaurants, merchants and close proximity to Montreal.” Subscribe to the Horse Sport newsletter and get an exclusive bonus digital edition! Opening week, Concours Hippique de Pépinière, will feature the Pépinière Grand Prix, Presented by Sandridge Saddlery and System Fencing, which will act as a qualifier for the Jump Canada Cup, on Saturday, May 21.  Sunday, May 22, brings the first annual Gladys Adam Hunter Derby, presented by Chateau Vaudreuil.  Held on the grass grand prix field, the Gladys Adam Hunter Derby will challenge horses and riders to negotiate the wide array of natural obstacles, including a bank. For more information, please visit Tags: Pépinière Horse Show, St. Lazare Horse Show, We’ll send you our regular newsletter and include you in our monthly giveaways. PLUS, you’ll receive our exclusive Rider Fitness digital edition with 15 exercises for more effective riding. Both Saturdays of competition will feature a JustWorld Horseless Horse Show and party to benefit JustWorld International, a not-for-profit, humanitarian organization working as a catalyst for positive change in the developing world by helping impoverished children.  The third annual ‘Agrocentre Belcan/Agribrands Purina Hockey Night in St. Lazare’ will also be held with all aspiring or former hockey players, regardless of skill level, invited to participate. The Pépinière and St. Lazare Horse Shows run daily from May 18 to 22 and May 25 to 29 at Eastwood Equine, 4170 Chemin Ste. Angelique in St. Lazare. Email* More from Horse Sport:Christilot Boylen Retires From Team SportAfter an exemplary career as one of Canada’s top Dressage riders, seven-time Olympian Christilot Boylen has announced her retirement from team competition.2020 Royal Agricultural Winter Fair CancelledFor only the second time in its history, The Royal Agricultural Winter Fair has been cancelled but plans are being made for some virtual competitions.Royal Agricultural Winter Fair Statement on 2020 EventAs the Province of Ontario starts to reopen, The Royal’s Board and staff will adhere to all recommendations put forward by government and health officials.Government Financial Assistance for Ontario FarmersOntario Equestrian has recently released this update of several financial assistance packages available, including those for farm business.last_img read more

Maryland officer charged with murder in shooting death of handcuffed man

first_imgPrince George’s County Police Department via Twitter(TEMPLE HILLS, Md.) — A Maryland police officer was charged with murder on Tuesday after fatally shooting a suspect who was handcuffed at the time, according to police.Prince George’s County Police Department officer Michael Owen Jr. was charged with second-degree murder in the shooting death of 43-year-old William Green while he was cuffed in the front seat of the officer’s cruiser with his hands behind his back, police said.Owen, a 10-year veteran of the force, fired seven shots at the man after arresting him in Temple Hills, about 50 miles southwest of Baltimore, on Monday night. The shooting unfolded as Owen and an unidentified second officer were responding to a call about a man slamming his vehicle into parked cars, police said.Green, who was suspected to be under the influence of PCP at the time, was removed from this car, handcuffed and placed in the front seat of the police cruiser while Owen and another officer waited for a drug recognition expert, police said.At some point, Owen got into the driver’s seat of the cruiser beside Green. The department said the officer opened fire a “short time later,” but it’s unclear why, according to the department.Owen and the unidentified second officer removed Green from the cruiser and provided aid until medics arrived, police said. He was transported to a local hospital where he died a short time later.“This is the most difficult moment of my tenure as your chief of police,” Hank Stawinski told reporters Tuesday evening. “I’m unable to come to our community this evening and provide you with a reasonable explanation for the events that occurred last night. I have concluded what happened last night is a crime.”“There are no circumstances upon which this outcome is acceptable and I want to extend my heartfelt sorrow and sympathies to the Green family,” he added.The department said it is investigating why the officer may have opened fire even though the man was restrained. There was no body camera on during the incident.Family members held a vigil for Green near the scene in Temple Hills on Tuesday.“They shot my son and it’s not right,” Green’s mother, Brenda Green, told Washington, D.C., ABC affiliate WJLA-TV. “How you gonna shoot somebody sitting in a front seat of a car in handcuffs and with a seat belt on? Why would you do that?”Green’s fiancee, Sandra Mathis, said the family is determined to “get to the bottom” of what happened.“We want to know why our loved one was brutally shot in a police car, handcuffed, seat-belted and in the front seat,” Mathis told WJLA. “We have questions that’s not being answered. We want to get to the bottom of this.”Owen was charged with second-degree murder, voluntary and involuntary manslaughter, first-degree assault and use of a firearm in the commission of a crime of violence.He was still in police custody as of late Tuesday. It’s unclear if he has retained an attorney.Copyright © 2020, ABC Audio. All rights reserved.last_img read more

Cory Wong Debuts New Variety Show, Releases “Coming Back Around” Ft. Cody Fry [Stream]

first_imgCory Wong celebrated the premiere of his new Cory and The Wongnotes variety show on Thursday, along with the arrival of a new single entitled “Coming Back Around”.The first of eight episodes as part of Wong’s new performance and sketch comedy-based web series debuted for free on Wong’s YouTube page. Thursday’s episode notably featured an interview and performance alongside special guest Cody Fry, who also sings and plays guitar on “Coming Back Around”. Fry was also a guest vocalist on Wong’s 2020 albums Elevator Music For An Elevated Mood and Live In Amsterdam.Watch Thursday’s episode and stream Wong’s new single below.Cory and The Wongnotes – Episode 1[Video: Cory Wong]Cory Wong – “Coming Back Around” feat. Cody Fry[Video: Cory Wong]“I’ve always been a fan of late-night TV, specifically late-night talk shows. But as a musician, I’ve selfishly wanted more focus on the music and the musicians! So I figured I’d start my own show that does it,” Wong said in a press statement about his latest creative venture. “For years I have worked as a bandleader and music director for other projects, but doing it for my own show has been a real pleasure. Beyond the musical aspect, it has been a creatively energizing endeavor to write and act in sketches, and to take the wheel as host of the show. This is the most ambitious and creatively fulfilling project for me. I brought in some of my best friends and musicians that I know to create together and to interview them about their process.”New episodes of Cory and the Wongnotes are set to premiere every Thursday on Cory Wong’s YouTube page.last_img read more

Roblox weekly roundup: 30th September – 6th October

first_imgApologies folks, I missed a couple of episodes of our Roblox weekly roundup but we are back with a bang this week with some great Roblox games for you to play. This week we have three very different games to recommend so hopefully you’ll enjoy at least one of them!First up this week is The Really Easy Obby by GFink. I don’t normally play that many obbys as they tend to be overly similar. This one stood out due to its innovative use of obstacles and puzzles that I haven’t seen in any other obbys. Don’t be fooled by the name either, it’s anything but easy. If you’re looking for some other obbys to play check out our top 5 obbys to play right now article.Credit: Roblox CorpNext up is Natural Disaster Survival by Stickmasterluke. As the name suggests your aim here is to try and survive the various natural disasters that appear on the map to try and kill you. Disasters include hurricanes, a deep freeze and volcanic eruptions to name just a few. As you try and survive the structures on the map are gradually destroyed making survival no easy task.Credit: Roblox CorpFinally this week we have Be a Parkour Ninja by Aurarus. Imagine if you put Crouching Tiger Hidden Dragon into a Roblox game, that’s pretty much what you get here. The movement is what sets this game apart from other swordy games on Roblox. You move very fast, can scale great heights and jump around with ease. Armed with a choice of one of two swords (slow or fast), and shuriken, your aim is to simply kill as many of the other players before the timer runs down. This is by far the best game I’ve played on Roblox for ages and I’m looking forward to more maps being released.Credit: Roblox CorpThat’s it for this week, hopefully, you will like at least one if not all of our suggestions. Thanks for reading and we’ll be back next week with some more great recommendations.last_img read more

Orioles won’t air any 2018 games on local broadcast TV

first_imgFor the first time in club history, the Orioles won’t air a slate of games on local broadcast television this season.The Mid-Atlantic Sports Network will become the exclusive home of Orioles baseball with the exception of select games on national television, which could mean a few games airing on WBFF Fox 45 in Baltimore. It’s no secret that the number of contests shown on WJZ-TV had dwindled in recent years in favor of MASN, but the local CBS affiliate had still aired 20 Orioles games produced by the cable network last year.Washington Nationals games will also now be shown exclusively on MASN and MASN2 after a limited slate of contests had aired on a local broadcast channel in Washington in recent years.The decision is hardly unprecedented as regular-season Red Sox games haven’t aired on local broadcast TV in Boston for more than a decade, but the wealthy New York Yankees haven’t abandoned local broadcast TV and will air 21 games on WPIX this season.It’s an unfortunate development for local Orioles fans who don’t subscribe to cable or satellite TV as more and more people are “cutting the cord” in favor of streaming services. Making matters worse is the Orioles and MASN being so far behind other major league clubs with their archaic restrictions on in-market streaming.This measure is unlikely to move the meter in a dramatic way for the Orioles and MASN as you wouldn’t expect the disappearance of such a limited slate of local broadcasts would move anyone to suddenly subscribe to cable or satellite TV. However, the occasional game airing on WJZ likely served as a decent advertisement for the club in terms of enticing viewers to buy tickets for a game at Oriole Park at Camden Yards or giving them a preview of MASN’s product in the same way HBO offers free preview weekends from time to time.When you’re not airing any games on over-the-air TV and — even more concerning — continue to drag your feet over in-market streaming policies, it’s easy to argue that you’re protecting your cable network and rights fees in the present day. However, the long-term danger is being out of sight and eventually out of mind in an age when TV-viewing habits are rapidly evolving.last_img read more

Fantasy Injury Updates: Mike Evans, Cooper Kupp, Stefon Diggs, more affecting Week 9 WR rankings

first_imgTyreek Hill injury updateHill suffered a groin injury last week against the Broncos, but he practiced in full on Wednesday, according to Chiefs beat writer Matt Derrick. Barring any setback, it seems that Hill will be able to play.The biggest impact from Hill likely playing is that Chris Conley and Demarcus Robinson won’t get a chance to start. That’s not too big a deal though, as they were fringe fantasy options anyway.Sammy Watkins could also benefit from Hill coming back, as Hill will matchup with stud corner Denzel Ward. That will make Watkins face T.J. Carrie, and he should be able to beat the former Raider. Because of this, Watkins’ status as a WR2/3 this week won’t be impacted. Week 9 Rankings:Quarterback | Running Back | Wide Receiver | Tight End | D/ST | KickerIs Mike Evans playing Week 9?UPDATE: Evans returned to practice on Thursday. That’s a good sign for him and if he can continue to practice without suffering setbacks, he should have a chance to play on Sunday against the Panthers.Evans suffered a knee injury late in the Bucs’ comeback attempt against the Bengals last week. It wasn’t exactly clear at the time what the extent of the injury might be, but Evans missed practice on Wednesday, according to Greg Auman of The Athletic. That will make his status going forward this week critical to watch, as he is starting to look truly questionable for Sunday’s game.In the event that Evans can’t suit up because of the injury, DeSean Jackson and Chris Godwin would immediately move up in our WR rankings. The Panthers secondary hasn’t been great this year, and the Buccaneers figure to throw the ball frequently against them given their lack of a running game. Jackson would be the big-play threat, and he has great chemistry with Ryan Fitzpatrick, while Godwin would be more of a possession guy/TD threat (he had a score in each of Fitzpatrick’s first three starts of the season).It’s also possible that O.J. Howard and Cameron Brate could see more action if Evans is out. The Panthers are the worst team in the league against TEs, allowing the most fantasy points per game, so they could end up being TD threats and seeing more targets if Evans is out. No matter what, the Bucs passing game can be trusted, even if Evans can’t get on the field for Week 9. The matchup is just too good and the team has a lot of offensive weapons.MORE WEEK 9: Waiver wire pickups | How You’ll Lose | Preview PodcastIs Cooper Kupp playing Week 9?Earlier in the week, it was reported by Vincent Bonsignore of The Athletic that Sean McVay said Kupp had a “good chance” of playing against the Saints. It’s looking like that prediction may come into fruition.Kupp was able to return to practice on Wednesday, albeit in a limited fashion. If he continues to practice without suffering any setbacks, that may mean he’ll be ready to return in Week 9. Of course, it would be nice to see him upgraded to full participant at some point before Sunday, but for now, things are still trending in the right direction for Kupp. He’s a high-end WR2/WR1 in this favorable matchup.WEEK 9 DFS CASH LINEUPS: Yahoo | FanDuel | DraftKingsStefon Diggs injury updateUPDATE: Diggs officially missed Thursday’s practice, per Chad Graff of The Athletic. Friday now becomes crucial for him, as he will likely need to be at least limited to play against the Lions.Diggs popped up on the injury report this week with a rib injury, and he sat out of practice on Wednesday,  according to the Vikings’ official Twitter. Diggs suffered the injury in the team’s Week 8 loss to the Saints, but it didn’t impact his ability to stay on the field.It’s possible that this could just be a maintenance day for Diggs, but his practice status on Thursday will enlighten us a lot more. If he can get back on the field in a limited capacity, that will quell concerns over his availability for this week’s matchup against the Lions.If Diggs can’t suit up because of the rib injury, it’s likely that Laquon Treadwell and Aldrick Robinson would receive more snaps. Neither would be a particularly appealing fantasy option, but there’s a chance that Treadwell could catch a TD. So, he might see a bump in our WR rankings if Diggs can’t see the field. Still, it seems more likely that the Vikings will rely on Adam Thielen and Kyle Rudolph as their top targets, so they would continue to be top fantasy options. WEEK 9 PPR RANKINGS: Running back | Wide receiver | Tight endAllen Robinson injury newsAfter missing last week’s contest with a groin injury, Robinson was held out of practice on Wednesday with the same issue. Unless something changes in the near future, it looks like Robinson may be forced to miss his Week 9 contest with the Bills, as well.If Robinson is out, Taylor Gabriel and Anthony Miller will be the top options in the Bears receiving corps, but they’re still WR3/FLEX plays (at best). Tight end Trey Burton and RB Tarik Cohen will also see some targets, but Cohen is the better bet to be productive of that duo, as the Bills have been good against TEs this year.MORE WEEK 9 DFS: Values | Stacks | Lineup BuilderIs Keke Coutee playing in Week 9?Coutee was limited in practice on Wednesday as he continues to return from a hamstring injury that has hampered him for most of the season. Considering that he had a mini-bye to return from the injury, getting in a limited practice early in the week seems like a good sign.Though the acquisition of Demaryius Thomas put a damper on Coutee’s overall value, there’s still a good chance that if he’s on the field, he will see a solid target share. He was trending toward being the team’s No. 2 receiver even with Will Fuller in the lineup, as he is a great slot/possession guy. If Coutee plays, he can be trusted as a low-end WR3/FLEX because of his high volume of targets.  The receivers across the NFL are starting to get banged up. Mike Evans suffered a knee injury on Sunday, while Cooper Kupp is trying to return from one. Stefon Diggs has also surfaced on the injury report after suffering a rib injury against the Saints. Meanwhile, Allen Robinson and Keke Coutee are both trying to avoid multi-week absences in their respective recoveries. These injuries might cause us to update our Week 9 WR rankings and could create some unexpected start ’em, sit ’em decisions for fantasy football owners, especially with so many teams on bye.As more injury news from around the league comes in, we’ll provide updates and keep you posted on all the latest developments. You can also follow us on Twitter @SN_Fantasy for more fantasy advice and updates. For Thursday night updates on Matt Breida, go here. For the latest on C.J. Beathard, click here.last_img read more

‘Show f******* balls’ – Liverpool star reveals Klopp’s incredible team talk

first_img Getty whoops gameday cracker Arsenal transfer news LIVE: Ndidi bid, targets named, Ozil is ‘skiving little git’ Liverpool update ‘Champions Wall’ after ending 2019 as European and world champions latest Lampard appears to aim dig at Mourinho for handling of Salah and De Bruyne at Chelsea After falling to a 3-0 defeat at Camp Nou in the first leg, the Reds seemed to be heading out of the Champions League at the semi-final stage.Without Mohamed Salah and Roberto Firmino, the task seemed too big for Klopp’s side to overcome.But doubles from Divock Origi and Giorginio Wijnaldum sent Liverpool to the final in Madrid on June 1.And Dejan Lovren, who was on the bench for the Merseyside miracle, believes it is all down to the words of wisdom from their charismatic German. MOST READ IN FOOTBALL 2 The average first-team salaries at every Premier League club in 2019 revealed Dejan Lovren revealed what Jurgen Klopp said to inspire Liverpool Divock Origi celebrates the winner at Anfield center_img SORRY Liverpool’s incredible comeback victory against Barcelona is unlikely to be forgotten by fans anytime soon.And it seems neither will Jurgen Klopp’s rather unique speech which inspired the 4-0 win at Anfield. Boxing Day fixtures: All nine Premier League games live on talkSPORT JIBE Liverpool news live: Klopp reveals when Minamino will play and issues injury update Did Mahrez just accidentally reveal Fernandinho is leaving Man City this summer? “Congratulations to Klopp,” he told Liverpool’s official website .“Before the game he did an amazing speech.“It was something brilliant and I think he lifted us so high. It was just ‘Believe! Put it in your mind that we can do it’. It was something that we’ve never heard before.“He said: ‘Boys, believe. One or two goals, even if we don’t score in the first 15, 20 minutes, believe in the 65th, 66th, 67th minute that we can score, and then with Anfield behind us, trust me guys, we can do it. TROPHY 2 LATEST Sky Sports presenter apologises for remarks made during Neville’s racism discussion “‘We did it once against Dortmund, we can do it tonight. Just show f******* balls tonight.’ And we did it!”Liverpool will play either Ajax or Tottenham in the Champions League final. Tune into talkSPORT this evening to hear full commentary of their semi-final second leg clash, live from Amsterdam!last_img read more