Novartis buying AveXis for $8.7 billion to strengthen gene therapy capabilities

first_imgPharma About the Author Reprints [email protected] Adam Feuerstein GET STARTED By Adam Feuerstein April 9, 2018 Reprints @adamfeuerstein Log In | Learn More Tags biotechpharmaceuticals Novartis buying AveXis for $8.7 billion to strengthen gene therapy capabilities Unlock this article by subscribing to STAT+ and enjoy your first 30 days free! GET STARTED Senior Writer, Biotech Adam is STAT’s national biotech columnist, reporting on the intersection of biotech and Wall Street. He’s also a co-host of “The Readout LOUD” podcast. Novartis is acquiring AveXis for $8.7 billion to strengthen its gene therapy unit, adding a promising but still experimental treatment targeting a fatal childhood disease.AveXis, a small biotech based in a north Chicago suburb, is being purchased for $218 per share, or an 88 percent premium to Friday’s closing stock price, Novartis said. Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr. What’s included? What is it? STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.last_img read more

‘Disruptive weather’ predicted as Storm Ciara set to hit Laois this weekend

first_img ‘Disruptive weather’ predicted as Storm Ciara set to hit Laois this weekend Laois Councillor ‘amazed’ at Electric Picnic decision to apply for later date for 2021 festival WhatsApp Facebook Pinterest News Twitter By Megan Shiel – 6th February 2020 Previous articleTalking Politics: Kildare South, borders and the battle of BirrNext articleCamross woman named as Laois Camogie volunteer of the year for 2019 Megan ShielMegan is currently studying English and New Media at the University of Limerick. A Raheen native, she’s happiest when talking sport, especially soccer but just don’t mention the 2019 champions league final Facebook Twitter Home News ‘Disruptive weather’ predicted as Storm Ciara set to hit Laois this weekend News A storm is brewing and is set to hit Laois this weekend.Hail, thunder and gale force winds are predicted with the worst of it set to hit on Saturday night and into Sunday.Ireland’s Weather Channel’s Cathal Nolan has said “As expected, Storm Ciara has been officially named by the UK Met Office.“It will bring disruptive weather conditions across large parts of the country during Saturday and Sunday, with strong winds and a risk of significant coastal flooding in some locations.”Met Éireann have said “Unsettled weather is expected to develop across Ireland and Northwest Europe this weekend.“The change will occur as very cold air sweeps out of Canada into the North Atlantic creating a sharp temperature contrast in the atmosphere over the ocean.“This temperature contrast will result in the intensification of the jet stream over the North Atlantic, which will drive vigorous areas of low pressure towards Ireland.“After a period of rather quiet weather, the change to unsettled mobile conditions will occur during Friday (Feb 7) as wet and windy weather moves in from the Atlantic.“A further spell of heavy rain is expected on Saturday (Feb 8) and this will be accompanied by strong and gusty winds with a possibility of Status Yellow warnings.“Weather conditions are expected to deteriorate further on Sunday (Feb 9) as Storm Ciara (named by the UK Met Office on Wednesday 5th February) tracks to the north of Ireland.“Storm Ciara is forecast to be a vigorous Atlantic storm system with an expansive wind-field.“There is a growing consensus that Sunday will be an extremely windy day across Ireland and the UK with widespread heavy rain, squally showers and with gales or storm force winds around our coasts.”SEE ALSO – Laois Open Door Theatre in full swing with rehearsals for new play Bizarre situation as Ben Brennan breaks up Fianna Fáil-Fine Gael arrangement to take Graiguecullen-Portarlington vice-chair role GAA TAGSCathal NolanMet EireannStorm Ciara 2020 U-15 ‘B’ glory for Ballyroan-Abbey following six point win over Killeshin RELATED ARTICLESMORE FROM AUTHOR Electric Picnic Pinterest WhatsApplast_img read more

SEC issues warning on custody deficiencies

IOSCO report sets out custody standards for investment funds Facebook LinkedIn Twitter Keywords CustodyCompanies Securities and Exchange Commission Share this article and your comments with peers on social media Related news CSA’s new rules enhance custody requirements on EMDs The U.S. Securities and Exchange Commission (SEC) Monday issued alerts to both firms and clients after its compliance examinations turned up significant deficiencies concerning custody issues at investment advisory firms. The SEC put out a “risk alert” on compliance with its custody rule for investment advisors; and, it also issued a bulletin to investors about the rule, which is designed to protect advisory clients from theft or misuse of their funds and securities. The alert from the SEC’s Office of Compliance Inspections and Examinations (OCIE) notes that the recent findings of custody deficiencies have resulted in a range of actions, including firms taking remedial measures, such as enhancing their compliance procedures, changing their business practices, or devoting more resources to custody issues. It has also made referrals to enforcement. The investor bulletin, which was issued by the SEC’s Office of Investor Education and Advocacy, explains the requirements of the custody rule, including the requirement for custodians to send account statements to investment advisory clients at least every quarter. It also stresses that the rule is not a substitute for investors’ oversight and monitoring of their investments. “Investors should always ask questions — including questions about the custody issues discussed in this Investor Bulletin — when considering an investment,” said OIEA director, Lori Schock. “Asking questions and monitoring investments are key ways to protect yourself from investment fraud.” The OCIE reports that a review of recent examinations where significant deficiencies were identified showed custody-related issues in about one-third of the firms examined. The deficiencies included: firms failing to recognize that they have custody, such as situations where the advisor serves as trustee, or is authorized to make withdrawals from a client’s account; failure to meet the custody rule’s surprise examination requirements; and, failure to satisfy the rule’s qualified custodian requirements, such as commingling client, proprietary, and employee assets in a single account. “Because the safeguarding of assets is central to investor protection, it is critical that investment advisors follow our rules when they maintain custody of their clients’ funds,” said SEC chairman, Elisse Walter. “We take deficiencies in this area very seriously and want to put advisors on alert about the importance of complying with the custody rule,” said OCIE director, Carlo di Florio. “It is a key component of our investment advisor examination program.” James Langton read more

Nick Simone to retire as president of QFS

first_img CI Financial CEO to retire Megan Harman BMO announces executive retirements Sheila Murray to retire from CI Financial in March Simone will continue to work with QFS in a consulting capacity in a newly created role as advisor relationship consultant following his retirement. He will help QFS expand existing relationships and develop new ones in this role while also assisting the MGA during the transition period after his retirement. QFS has prepared for Simone’s pending retirement in recent months by bringing on Larry Goldberg as chief operating officer in May 2016, according to Kevin Cott, CEO of QFS. The firm has also expanded the responsibilities of other members of the executive team, including Joseph Trozzo, vice president of sales, and Perry Villanueva, vice president of recruiting and advisor development. Cott says in a statement that he is preparing his three children to assume leadership of QFS in the coming years. Simone has been with QFS since April 2011. Prior to joining QFS, he was president of Walton Capital Management Inc. Photo copyright: jirsak/123RF Share this article and your comments with peers on social media Keywords Managing General Agencies,  Resignations and retirements Toronto-based managing general agency (MGA) Qualified Financial Services Inc. (QFS) announced on Wednesday that its president, Nick Simone, will be retiring from his position effective March 31. Related news Facebook LinkedIn Twitterlast_img read more

Jamaicans Will be Involved in Vision 2030

first_imgAdvertisements RelatedJamaicans Will be Involved in Vision 2030 FacebookTwitterWhatsAppEmail RelatedJamaicans Will be Involved in Vision 2030 Jamaicans Will be Involved in Vision 2030 Vision 2030November 5, 2007center_img Executive Director of the Planning Institute of Jamaica (PIOJ), Dr. Wesley Hughes, has said that the development of the plan, which will put Jamaica on a path to achieve developed country status by 2030, will have the full participation of Jamaicans from various sections of the society.Speaking at the launch of Vision 2030, the long-term strategic National Development Plan, on Wednesday (Oct. 31) at the Jamaica Conference Centre, Dr. Hughes said that the plan will reflect the aspirations of Jamaicans about their long-term future and only stands a chance of being successful based on this people-centred principle.“When we examine the history of Jamaica since Independence, we cannot discern any single national goal or strategy that unites the country across administrations, and which acts as a catalyst for development. That is why, from the beginning, we have seen this plan as a partnership and have sought to make the process of drafting and reviewing the plans as inclusive as possible. We want every Jamaican to know about this plan and be familiar with what it seeks to achieve because it will directly affect us all,” he stated.Mr. Hughes said he wanted Jamaicans in their different capacities throughout the country, to provide consensus on the way forward for the country as it embarks on the preparation of the 25-year National Development Plan. “We want Jamaicans to be aware of what is taking place and how this national initiative filters down to them at the community and individual levels,” he stated.He informed that to date, 30 task force teams, each comprising of experts in the respective fields, and charged with the development of sector strategic plans, “are working on various sector plans,” and have produced 26 preliminary drafts so far.The plan is being developed with broad-based support across every strata of the society. The PIOJ, in its role as the main planning agency in Jamaica, is leading and facilitating this collaborative process, incorporating the support from private sector groups, civil society and the Diaspora. A Plan Advisory Group (PAG) consisting of industry leaders, academia, as well as leaders from various sectors, will support the work of the PIOJ.“But more difficult work lies ahead, involving wider consultation, making strategic decisions about priorities, integrating the sector plans into a cohesive and internally consistent document with implementation and action plans, along with timelines and even budgets for the first few years,” he informed.Preparation of the draft plan started in January 2007 and will continue until March 2008. It will be tabled in the House of Parliament in April 2008, following which there will be further island-wide consultations, prior to finalization.Over the 15-month period, the PIOJ has planned a series of public consultations called the ‘PIOJ’s Dialogue for Development Series’. These will be organized at strategic locations, and will engage participants from the community, youth groups, public and private sector, non governmental organizations (NGOs) and other special interest groups. These will take the form of town hall meetings and discussions as part of the PIOJ’s Dialogue for Development Series.The launch was attended by representatives from the state, private sectors, students, media, church, the non-governmental organization (NGO) community and members of the diplomatic corps.The plan was officially launched by Prime Minister Bruce Golding. Story HighlightsExecutive Director of the Planning Institute of Jamaica (PIOJ), Dr. Wesley Hughes, has said that the development of the plan, which will put Jamaica on a path to achieve developed country status by 2030, will have the full participation of Jamaicans from various sections of the society.Speaking at the launch of Vision 2030, the long-term strategic National Development Plan, on Wednesday (Oct. 31) at the Jamaica Conference Centre, Dr. Hughes said that the plan will reflect the aspirations of Jamaicans about their long-term future and only stands a chance of being successful based on this people-centred principle.”When we examine the history of Jamaica since Independence, we cannot discern any single national goal or strategy that unites the country across administrations, and which acts as a catalyst for development. That is why, from the beginning, we have seen this plan as a partnership and have sought to make the process of drafting and reviewing the plans as inclusive as possible. We want every Jamaican to know about this plan and be familiar with what it seeks to achieve because it will directly affect us all,” he stated. RelatedJamaicans Will be Involved in Vision 2030last_img read more

Canada announces new funding in continued response to humanitarian crisis in Yemen

first_imgCanada announces new funding in continued response to humanitarian crisis in Yemen From: Global Affairs CanadaThe human cost of the ongoing conflict in Yemen is dire. That is why Canada is committed to ensuring that emergency relief quickly reaches those most affected by the world’s worst humanitarian crisis.The human cost of the ongoing conflict in Yemen is dire. That is why Canada is committed to ensuring that emergency relief quickly reaches those most affected by the world’s worst humanitarian crisis.Today, the Honourable Karina Gould, Minister of International Development, at the Virtual High-Level Pledging Event for the Humanitarian Situation in Yemen, convened by the UN, Sweden and Switzerland, announced $69.9 million in funding in continued response to the humanitarian needs of conflict-affected people in Yemen in 2021.This new funding will be provided to UN agencies, the Red Cross, and other non-governmental organizations. With Canada’s support, its humanitarian partners will provide life-saving food and support health care, clean water and sanitation. In line with its Feminist International Assistance Policy, Canada’s humanitarian assistance will also focus on the urgent needs of women and girls, who are disproportionately affected by the ongoing conflict and humanitarian crisis in Yemen.During the event, Minister Gould emphasized Canada’s deep concern for the deteriorating food security situation in Yemen and advocated for unimpeded access for humanitarian assistance, in accordance with international humanitarian law.Quotes“Yemen is undergoing the world’s worst humanitarian crisis, and its people deserve decisive action. Their suffering must end, and their rights and dignity must be protected. We must do everything possible to make this happen.”– Karina Gould, Minister of International DevelopmentQuick factsSince the start of the conflict in 2015, Canada has provided over $295 million in humanitarian funding to support food assistance, clean water and sanitation, shelter, protection and health care, including sexual and reproductive health services.In addition to humanitarian support, Canada is investing in peace and stability in Yemen. Since December 2018, Canada has provided over $22 million in peace and security assistance in Yemen to support the UN-led peace process. /Public Release. This material comes from the originating organization and may be of a point-in-time nature, edited for clarity, style and length. View in full here. Why?Well, unlike many news organisations, we have no sponsors, no corporate or ideological interests. We don’t put up a paywall – we believe in free access to information of public interest. Media ownership in Australia is one of the most concentrated in the world (Learn more). Since the trend of consolidation is and has historically been upward, fewer and fewer individuals or organizations control increasing shares of the mass media in our country. According to independent assessment, about 98% of the media sector is held by three conglomerates. This tendency is not only totally unacceptable, but also to a degree frightening). Learn more hereWe endeavour to provide the community with real-time access to true unfiltered news firsthand from primary sources. It is a bumpy road with all sorties of difficulties. We can only achieve this goal together. Our website is open to any citizen journalists and organizations who want to contribute, publish high-quality insights or send media releases to improve public access to impartial information. You and we have the right to know, learn, read, hear what and how we deem appropriate.Your support is greatly appreciated. All donations are kept completely private and confidential.Thank you in advance!Tags:Canada, conflict, crisis, Emergency, Government, health services, Human, Humanitarian, Minister, Red Cross, reproductive health, security, Sweden, Switzerland, UN, world, Yemenlast_img read more

Clark County Public Health launches new interactive tool for exploring health data

first_imgClark County Public Health launches new interactive tool for exploring health dataPosted by ClarkCountyToday.comDate: Monday, November 16, 2020in: Community Newsshare 0 Through data visualized on maps and charts, users can explore how health and the circumstances and environments that influence health are distributed across the countyVANCOUVER – Clark County Public Health launched a new online data exploration tool called the Healthier Clark County InfoMap. The interactive tool offers a new way of learning about health issues and how they impact people in Clark County. Through data visualized on maps and charts, users can explore how health and the circumstances and environments that influence health are distributed across the county.Topic areas in the InfoMap include demographics and social factors that influence health, such as income, education and housing. The tool also features maps and data for several public health focus areas, including maternal health, chronic disease, and behavioral health. Image courtesy of Clark County Public HealthTopic areas in the InfoMap include demographics and social factors that influence health, such as income, education and housing. The tool also features maps and data for several public health focus areas, including maternal health, chronic disease, and behavioral health. Image courtesy of Clark County Public Health“Public Health is excited to make health-related data more easily accessible to the community through the Healthier Clark County InfoMap online tool,” said David Hudson, Healthy Communities program manager. “This tool will be available at your fingertips 24 hours a day, seven days a week.” Topic areas in the InfoMap include demographics and social factors that influence health, such as income, education and housing. The tool also features maps and data for several public health focus areas, including maternal health, chronic disease, and behavioral health. Public Health envisions the InfoMap serving as a planning tool to support public health, schools, community-based organizations, policy makers, and community members. Data from this tool can be used to identify priorities and prevention efforts to address health concerns, apply for grant funding, promote policy and legislative priorities, and to learn more about places in Clark County.The tool and a short video demonstrating how to navigate InfoMap are available on the Public Health website, https://www.clark.wa.gov/public-health/healthier-clark-county-infomap.Information provided by Clark Co. WA Communications.AdvertisementThis is placeholder textTags:Clark CountyVancouvershare 0 Previous : Rep. Paul Harris re-elected to House Republican leadership role Next : Vancouver accepting applications for up to $6.72 million in Affordable Housing Community Development grantsAdvertisementThis is placeholder textlast_img read more

CU-Boulder biologist Leslie Leinwand elected to American Academy of Arts and Sciences

first_imgCategories:AcademicsScience & TechnologyCampus CommunityNews Headlines University of Colorado Boulder biologist Leslie Leinwand has been selected as a member of the 2014 class of the American Academy of Arts and Sciences, which honors the leading “thinkers and doers” from each generation, including scientists, scholars, writers and artists.Leinwand—chief scientific officer for CU-Boulder’s BioFrontiers Institute and a professor of molecular, cellular and developmental biology—is an expert in cardiovascular disease.“Her election to the American Academy of Arts and Sciences is an outstanding recognition of Leslie’s scientific contributions to understanding the biology of the heart,” said BioFrontiers Institute Director Tom Cech.“Leslie has made a career of fearlessly and creatively approaching challenges, like heart disease, by searching for answers beyond her field and beyond what we think could be possible,” said Cech, also a distinguished professor of chemistry and biochemistry. “This unique view of science also is giving the students in her lab and in her classroom the tools and perspectives they will need to solve the biomedical challenges of the future.”Leinwand’s research opens the door to the possibility of personalized treatment for heart disease. She has shown that the mechanisms of heart disease differ between males and females and that the genetic risk of the disease is impacted by both gender and diet.Leinwand’s lab also has studied the blood of Burmese pythons, which has the unusual property of greatly increasing the size of the snake’s internal organs, including the heart, after a large meal, a feature that could also have implications for combating human heart disease. Her research has shown that this enlargement shares features with the response of the human heart to chronic exercise.Among the 204 new members of the academy, who will be inducted at an October ceremony in Cambridge, Mass., are Nobel Prize-winning chemist Dan Shechtman, Pulitzer Prize-winning journalist Ann Marie Lipinski, atmospheric scientist Inez Fung, novelist and screenwriter John Irving, actor and director Al Pacino, musician Ralph Stanley and artist Kerry James Marshall. The full list of members is online at https://www.amacad.org/members.aspx.With Leinwand’s election, a total of 29 CU-Boulder faculty members have been inducted into the academy.The American Academy of Arts and Sciences was founded in 1780, and members have included George Washington, Benjamin Franklin, Daniel Webster, Ralph Waldo Emerson, Albert Einstein and Winston Churchill.Contact: Leslie Leinwand, [email protected] Laura Snider, CU media relations, [email protected] Share Share via TwitterShare via FacebookShare via LinkedInShare via E-mail “Her election to the American Academy of Arts and Sciences is an outstanding recognition of Leslie’s scientific contributions to understanding the biology of the heart,” said BioFrontiers Institute Director Tom Cech.center_img Leslie Leinwand visits her lab in the Jennie Smoly Caruthers Biotech Building at the University of Colorado Boulder. (Photo by Casey A. Cass/University of Colorado) Published: April 23, 2014 last_img read more

GUARANTEED Wine Stability, with ZERO Additives and ZERO Wine Loss!

first_imgVineyard/GrowingWinemaking/OenologyFor a full list of exhibitors, go to www.unifiedsymposium.org/trade-show. You can also follow what’s happening on the trade show floor and conference sessions on twitter #UWGS.Advertisement Pinterest ReddIt Share Previous articleStop by Our Booth to See Our Air Pump “Flip”!Next articleAuction of Washington Wines’ August 2019 Private Barrel Auction to Feature Record Number of Exclusive Wine Lots Trade Show Guide Facebook Twittercenter_img Linkedin TAGSCrossflow MicrofiltrationoenologySTARS MobileSTARS XFTartrate StabilizationWinemaking/Oenology Home Trade Show Guide UWGS 2019 GUARANTEED Wine Stability, with ZERO Additives and ZERO Wine Loss!Trade Show GuideUWGS 2019GUARANTEED Wine Stability, with ZERO Additives and ZERO Wine Loss!By Trade Show Guide – January 15, 2019 70 0 Email AdvertisementFind out how you can get GUARANTEED Wine Stability, with ZERO Additives and ZERO Wine Loss!OENODIA (Booth #2406) will be featuring information on their full STARS Line including the new STARS XF, which combines Crossflow Micro-filtration with their exclusive STARS (Selective Tartrate Removal System) process for TARTRATE STABILIZATION and pH ADJUSTMENT.  Oenodia, one of the world’s leading specialists in membrane-based treatments for the wine and agri-business communities, has initiated the next step in the evolution of wine processing.STARS XF offers a Single-Pass, In-Line Clarification, Filtration, and Tartrate Stabilization process by allowing Centrifuge, Crossflow (XF) and STARS systems to communicate with each other.   STARS-XF which offers the combination of Crossflow with Tartrate Stabilization is the first step of the evolution and is now exclusively available from Oenodia North America.Register your interest in our STARS Mobile Service now operating three units, delivering STARS Stab, STARS pH and now STARS XF to your winery door.OENODIAUWGS Booth: 2406OENODIA is the oenology division of Eurodia Industrie S.A, (France) one of the world’s leading specialists in membrane-based treatments for the agri-food industry.OENODIA provides membrane based eco-processes used for tartaric stabilization, acidification, de-acidification, cross-flow filtration and de-alcoholization of wines.OENODIA’S STARS Line delivers a selection of membrane-based technologies, utilizing their exclusive Electrodialysis technique that safely and effectively removes wine tartrates, and has been proven to enhance wine quality, save power, eliminate wine loss and works with very large volumes.  STARS is available in stationary units and via OENODIA’s STARS Mobile Service which delivers the technologies right to your winery door.For more information call 707-486-4651 or visit us online at www.oenodia.us.Trade Show Guide Explore the 2019 Unified Wine & Grape Symposium featured exhibitors:Business ManagementHuman ResourcesInfrastructureLogisticsMarketingPackagingProductionProduction ServicesSalesTasting Roomlast_img read more

Alcatel plans new device launches at MWC

first_img LIVE FROM CES 2018, LAS VEGAS: TCL Communication revealed plans to launch a new global portfolio of Alcatel smartphones at Mobile World Congress, with a focus on delivering high end specs at affordable prices.Brad Molen, TCL’s senior manager of communications for Alcatel in North America, told Mobile World Live the company will debut three new smartphone lines at the show: the 5 Series, 3 Series and 1 Series.Molen was tight lipped on the exact specs of the devices, but highlighted phones in all three line-ups will offer 18:9-ratio displays and fingerprint sensors on the rear casing. All devices in the 5 Series will be priced at under $300, the 3 Series less than $200 and 1 Series units less than $100, he added.The goal of the new portfolio is to make flagship-style design and features more broadly accessible.“What we’re hoping to do in 2018 is put a refocus on product design and streamlining our portfolio,” Molen explained: “So instead of having all these different series and different names just trying to keep it simple.”Molen said more device details, including colour variations, will be unveiled at MWC.Jason Gerdon, a senior manager of communications at TCL, said Alcatel will continue to offer devices through existing partners, but stopped short of revealing which operators will offer the new models. Previous ArticleTCL wants to push BlackBerry beyond enterpriseNext ArticleVerizon CTO vows to beat AT&T to 5G HomeDevicesNews Alcatel plans new device launches at MWC Related AddThis Sharing ButtonsShare to LinkedInLinkedInLinkedInShare to TwitterTwitterTwitterShare to FacebookFacebookFacebookShare to MoreAddThisMore 11 JAN 2018 Researchers crack secret to self-repairing screens Diana is Mobile World Live’s US Editor, reporting on infrastructure and spectrum rollouts, regulatory issues, and other carrier news from the US market. Diana came to GSMA from her former role as Editor of Wireless Week and CED Magazine, digital-only… Read more Diana Goovaerts center_img Author Devices TCL eyes value sector with CES duo, teases 2021 range Earwear, wearable bands set for 2021 boom Tags AlcateldevicesTCLlast_img read more