McClaughry: The real drug price problem

first_imgby John McClaughry This week will likely see a Trump initiative to drive down pharmaceutical prices, and passage of a bill in Montpelier (S.175) to again plunge Vermont into the arduous (and illegal) process of importing prescription drugs from Canada.  The industry has understandably fought furiously against Federal price controls and the importation of American drugs from countries that imported them at controlled prices. It is clear to them that when the government decrees the price at which they must sell their products, those producers are on the road to economic extinction. But these battles never get to the root cause, not only of high pharmaceutical prices, but of the denial of the best possible health of all Americans. That root cause is the 1962 Kefauver-Harris Amendments to the Food, Drug and Cosmetic Act.Before 1962, manufacturers could market new drugs if, within six months, the FDA did not find them to be unsafe. The galvanizing force behind the Amendments was the thalidomide crisis.Thalidomide was a European drug created as a sleep aid, and then found useful to alleviate morning sickness in pregnancy. Tragically, it also caused deformities in babies. The FDA correctly banned it as unsafe, but not before the experimental use of samples had resulted in seventeen deformed babies in the US.Faced with the horrifying visuals on television, Congress seized the only readily available legislation – Senator Kefauver’s bill – and ran it through at flank speed. It gave the FDA “unprecedented control over the entire drug development process in the hopes that drugs not only would be safe, but would also be effective, advertised accurately, and manufactured carefully.”Those are the words of Dr. Mary Ruwart (PhD biophysics), from her new book Death By Regulation. She explains: “In the 1960s humanity was poised on the brink of a Golden Age of Health. Infection, the primary cause of death in the early 20th Century, had been largely vanquished by antibiotics, improved nutrition, and sanitation. Many vitamins had been isolated and manufactured. Their pivotal role, not only in preventing the classical deficiency diseases but also maintaining optimal health, was gaining increasing recognition.”But the 1962 Amendments dramatically changed the prospect. Now, any new drug had to receive affirmative approval by the FDA, and that approval required proof of “effectiveness” for a defined condition.Now, gaining approval of a new drug requires what is called Phase 3 human effectiveness testing. The approval process takes up to fourteen years (!),  requires  –  literally – “a truckload of paperwork”, and when the costs of all the failures are added in, costs the applicant an average of $2.6 billion.The public is more interested in drugs that treat and cure problems, not just “contribute to maintaining health (i.e. prevention).”  To recapture that enormous investment in an approved new drug, the manufacturer must spend millions in high-pressure marketing to convince doctors and patients that it will cure a problem.New drugs are usually patented. In most cases, that gives the manufacturer around 20 years to recapture the costs of getting it approved and to market. But the 20 years runs from the date of the patent grant. If it takes 14 years to get FDA approval, the drug’s patent protection is only six years, after which generic versions undercut the price. Dr. Ruwart, who worked on drug development for Upjohn for 19 years, tells of promising drugs pulled out of the approval process when it appeared that there wouldn’t be enough time to recover the costs before the patent expired.Then there’s the interlocking of the drug industry with the FDA bureaucracy. Together they have become a cartel to keep down upstart innovators. Even a slight delay in winning FDA approval may allow a competitor to be “first to market” for a new type of drug. That’s worth  billions of dollars to the winner. Companies that irritate FDA bureaucrats can be destroyed by their inaction or the imposition of new requirements. The pharmaceutical industry is also supportive of their FDA partner’s ongoing efforts to harass natural products and dietary supplements manufacturers, whose products could result in healthier people and thus a smaller market for cures.What’s the solution? Repeal the 1962 Amendments. Let FDA prohibit unsafe products, and like Underwriters Laboratories certify products that meet its standards. Leave doctors free to prescribe safe products that they think will best serve their patients, FDA-certified or not.  Let competing herb, supplement, and vitamin marketers offer truthful information to doctors and the public, without (as FDA demands) defining those products into “drugs”.Perhaps the greatest value of Death by Regulation is its carefully documented explanations of the malign consequences of foolish, hurried, costly, government action that has caused treatment to displace prevention, created a giant anti-competitive cartel, defeated innovation, and indeed corrupted the government itself.John McClaughry is vice president of the Ethan Allen Institute ( is external)).last_img read more

Northeast Johnson County morning roundup

first_imgSmoothie King signs are up at its new location.Smoothie King takes out license. The Smoothie King that is planning to open in mid- October along Johnson Drive has taken out its business license with the city. Smoothie King will be opening in the former Blockbuster building. The menu features a long list of smoothies and other items.Two SM East students are Jostens finalists. Kelsey Cox and Laine Duckworth, both students at SM East, are finalists in the 2016 Jostens Adobe Design Contest. Only 10 students from high schools across the country qualified as finalists in the contest.CFD2 August calls near 200. The Consolidated Fire District No. 2 August report shows 193 calls for service from fire and rescue and 230 medical calls. The department also logged 1,115 training hours. The department responded to several water rescue calls during the storm in late August.Mission Coffee with a Cop Sept. 16. The next date for the Mission Police Department to hold Coffee with a Cop will be at 8 a.m. Sept. 16 at Twisted Sisters Coffee Shop on Johnson Drive.Northeast Johnson County morning roundup is brought to you by Twisted Sisters Coffee Shop on Johnson Drive. For updates on the latest blends and specialty drinks available, follow them on Facebook.last_img read more

Your Community: Women and Money Day offers a path to financial literacy

first_imgDeveloping the confidence and skills to manage your money are important steps for taking control of your finances. When you’re in control, finances become less stressful and you gain peace of mind knowing that your money is working for you, not the other way around. If you want to learn how to build a financial foundation that supports you into the future, join Johnson County Library for Women and Money Day. This day-long seminar is designed for women of all backgrounds, levels of financial knowledge and stages of life. Learn the basics of personal finance and the steps you can take to gain financial stability, knowledge and confidence – now and for a lifetime.Presenter Helaine Olen, co-author of The Index Card: Why Personal Finance Doesn’t Have to Be Complicated, starts off the day with a keynote address and book signing. An expert on money and society, Olen is an opinion writer for the Washington Post Opinions section. She’s been featured on “The Daily Show with Jon Stewart” and took part in Frontline’s Emmy award-winning “The Retirement Gamble.” She also writes the nationally syndicated personal finance advice column “Life and Money with Helaine,” and serves on the advisory board of the Economic Hardship Reporting Project.Saturday, October 129:15 am – 3:30 pmCentral Resource LibraryTopics for afternoon breakouts include credit scores and credit building, apps for money management, investing, and the importance of wills. All women attending can schedule a free credit report review or a full consumer credit counseling appointment with a Certified Housing and Consumer Credit Counselor at HCCI.Register online to reserve a handbook, continental breakfast and box lunch; or call 913.826.4600. There is no charge to attend and space is limited.Johnson County Library – Nurturing the Community’s Collective Wisdom This is placeholder text This post is currently collecting data…last_img read more

It’s not a website. It’s another branch

first_imgIntroducing a guest post from Keith Winn, VP Marketing of cuZOOM, and CU veteran!It’s taken some 100 years, others 50 years, or even less. To do what? Essentially to develop the “perfect” member experience. You know exactly what I am talking about. For years, the credit union industry has challenged the “impersonality” of big banks, and created a unique, caring, and helpful financial environment where the member, no matter what they walked in for, comes first.So, with that said, what happened with their websites? Perhaps when credit unions started building websites, they were simply non-interactive billboards. Fair enough. But that was over 20 years ago. Probably about the time many credit unions embarked to create that perfect member experience in their physical locations. What about member’s online experience? Unfortunately, even with all of the available new technology, recent surveys indicate most credit union websites are still years behind in meeting member expectations.Maybe it’s because we gave it a name: the virtual branch. Sounds like we would see Keanu Reeves with dark glasses dodging bullets in slo-mo in the lobby, or a techno-rave with colored lights and head banging sounds. For whatever reason, we got lost. And, yet, the answer is so simple.Think of your website as just another branch and design accordingly. When you walk in the front door of your branch, its very clear where the reception desk is, or the teller windows. There’s no posters and banners to distract you. When the receptionist asks how they can help, you are immediately directed to a person who can assist. It’s almost too easy. continue reading » 3SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblrlast_img read more

The Surprising Boost You Get From Strangers

first_imgSometimes a stranger—not a friend or a loved one—can significantly improve our day. A pleasant encounter with someone we don’t know, even a nonverbal one, can soothe us when no one else is around. It may get us out of our own head—a proven mood booster—and help broaden our perspective. “People feel more connected when they talk to strangers, like they are part of something bigger,” says Gillian Sandstrom, a psychologist and senior lecturer in the Department of Psychology at the University of Essex, in Colchester, England, who studies interactions between strangers. “Sure, my name is Sue,” the woman replied, smiling warmly. “What brings you to Boston?” I started to explain that I was on a business trip. Then the plane lurched violently, and I blurted out: “I might need to hold your hand, too.” We hadn’t spoken much during the flight, other than the usual pleasantries. But my seatmate seemed friendly. And I suddenly felt desperate for a human connection. We were five minutes into the worst turbulence I’d ever experienced—approaching Boston’s Logan International Airport in a severe winter storm—when I turned to the woman next to me and said: “Hey, would you mind chatting with me for a few minutes? I’m really nervous.” And yet most people resist talking to strangers, she says. They fret about the mechanics of the conversation—how to start, maintain or stop it. They think they will blather on and disclose too much—or not talk enough. They worry they will bore the other person. Sue took my hand in both of hers, patted it, and held on tight. In research studies, Dr. Sandstrom has shown that people’s moods improve after they have a conversation with a Starbucks barista or a volunteer at the Tate Modern art museum in London. She’s also found that people are happier on days when they have more interactions with acquaintances they don’t know well and that students enjoy class more when they interact with their classmates. They’re typically wrong. Dr. Sandstrom’s research shows people underestimate how much another person will like them when they talk for the first time. And in a study in which she asked participants to talk to at least one stranger a day for five days, 99% said they found at least one of the conversations pleasantly surprising, 82% said they learned something from one of the strangers, 43% exchanged contact information, and 40% had communicated with one of the strangers again, an indication they might be making friends. Read the whole story: The Wall Street Journallast_img read more

Going places – 14 December 2007

first_imgChris Januaryhas joined Bidwells as a partner in its London office, where he will be responsible for leisure and retail agency. January’s previous roles include head of retail and leisure agency at Gerald Eve and associate director of retail agency at St Quintin. Hollins Murray Grouphas appointed Paul Mitchell as chairman. Mitchell joins from Rickitt Mitchell, where he was managing director. Young Grouphas recruited Fraser Matthews to its portfolio team. Matthews joins after four years with the Bank of Scotland Investment Service, where he was a private client manager.Atisrealhas taken on Julian Gaynor as an associate director in its Chancery Lane office in London. Gaynor joins from Turner Morum, where he spent four years in the development consultancy department. The company has also appointed Andrew Price as director, to head up the valuation department in its Birmingham office. Price was previously a partner at Donaldsons. Emma Noblehas joined Brodies as an assistant solicitor. Noble, who has worked in banking and financial regulations for five years, was previously with Dundas & Wilson. Brodies has also recruited Robin Priestley as an associate in the property department. He joins from Anderson Strathern.Jonathan Bucklehas been recruited by GVA Grimley to head its retail and leisure services team in Leeds. Buckle, who has worked in the industry for 11 years, will be based in Newcastle.David Jacksonhas been appointed as a partner in asset and property management in Drivers Jonas’s London office. Jackson has previously worked for Montagu Evans and LaSalle Investment Management and has more than 20 years’ experience in the asset management of commercial property.Hamptons Internationalhas recruited Kurt Fraser as international director. Fraser will work in the international residential agency’s London office, relocating from Lausanne, Switzerland, where he was European marketing director for Intrawest and Playground Real Estate.Philip Boothhas been recruited by Lambert Smith Hampton as a senior surveyor in its Maidenhead office. He joins from chartered surveyor Martin & Pole.Andrew Reedhas been appointed divisional director of NB Real Estate’s London retail agency team. Reed joins from Kitchen La Frenais Morgan, where he spent the last nine years letting shopping centres and undertaking retail agency across the UK.Savills Granitehas made three appointments at its New York office. Jennifer McKinnon and Marion Jones have been recruited as senior associates, and Marcella Grigg has been appointed as an associate. All three join from CB Richard Ellis: McKinnon was associate director for the financial consulting group at the Washington office; Jones was a senior associate in the New York office’s sales investment division; and Grigg was a business development analyst for CBRE’s Investment Properties Institutional Group. Storeys:ssphas appointed Adrian Gibbins as a surveyor in its corporate real estate team in Newcastle. He was previously director at Fairbairn Wild, and has also worked in the corporate real estate department at American Express. Damian Seddonhas been appointed managing director of Stewart Milne Homes. He will take charge of the housebuilder’s north-west of England division, based in Manchester. Seddon previously spent four years as Bovis Homes’ commercial director and six years as commercial manager at Redrow.Savillshas recruited Alistair Greenhalgh as associate director of its hotels team. Greenhalgh has spent more than eight years working with several hotel brands in the north-west.Brixtonhas appointed Stephen Armitage as asset management and customer service senior operations director at its B-Serv subsidiary. Armitage will take up his new role in February, after leaving his position as director of the public service division at Dunlop Haywards. Robin Goodchildhas been appointed honorary president of the Society of Property Researchers (SPR). Goodchild is head of European strategy and research at LaSalle Investment Management.Brigitte Bakerhas been recruited by business solutions provider Fasset as a sales executive to generate leads at its new Hersham Place Technology Park near Walton-on-Thames.Knight Frankhas unveiled a new senior management team to aid its expansion in the north-west. Partners David Porter and David Roper are based in the property consultancy’s Manchester office, and Charles Arden in Liverpool. Porter joined the north-west team in 2006 from Knight Frank’s national offices team in London. Roper, who has 28 years’ experience in the region, joined Knight Frank in 2000. Arden joined the company in 2005 and was made a partner this year.last_img read more

A CARICOM Youngster Excelling in the Maritime Industry

first_img CARICOM Youth Ambassadors’ Message – Caribbean… Share this:PrintTwitterFacebookLinkedInLike this:Like Loading… The American Caribbean Maritime Foundation (ACMF), in association with the Caribbean Association of National Training Authorities, and CARICOM Youth Ambassadors, launched the Maritime Linkup: Beyond Borders Webinars on the 19 August. There were subsequent sessions on 9 and 23 September, and additional ones will be held on 7 and 21 October. What CARICOM means to me – CARICOM Youth Ambassadors have… Maritime Webinars Coming for CARICOM Students The five-part webinar series focuses on connecting Caribbean youth with educational and professional opportunity in the maritime sector and blue economy. Girls Rock in the Maritime Industry Sep 30, 2020center_img Girls Rock in the Maritime IndustryThe American Caribbean Maritime Foundation (ACMF), in association with the Caribbean Association of National Training Authorities, and CARICOM Youth Ambassadors, launche the Maritime Linkup: Beyond Borders Webinars on the 19 August, with subsequent sessions on 9 and 23 September; and 7 and 21 October. The five-part webinar series focused on…September 2, 2020In “CARICOM”Global Maritime Leaders Engage CARICOM StudentsIn the wake of the COVID-19 pandemic which has pushed learning online across the region, a maritime webinar series will promote maritime education and job opportunities in shipping and logistics—one of the most important sectors in the Caribbean economy. The American Caribbean Maritime Foundation (ACMF), in association with the Caribbean…July 24, 2020In “Business”Maritime Webinars Coming for CARICOM StudentsIn the wake of the COVID-19 pandemic which has pushed learning online across the Region, a maritime webinar series will promote maritime education and job opportunities in shipping and logistics—one of the most important sectors in the Caribbean economy. The American Caribbean Maritime Foundation (ACMF), in association with the Caribbean…August 11, 2020In “Business”Share this on WhatsApp Aug 11, 2020 Jul 4, 2020 In this interview, Trevon Ferguson, a Maritime student, shares his experience of being in the Maritime Industry. He explains why he chose that field and how other young people can join and capitalise on the opportunities available via the blue economy. You may be interested in… Sep 2, 2020last_img read more

ABS Establishes Offshore Energy Center in Huston, USA

first_imgABS, the leading provider of classification services to the global offshore industry, is establishing an office in Houston’s Energy Corridor near the intersection of Interstate 10 and Highway 6.The new facility will co-locate members from ABS engineering, project management, technology and business management, allowing ABS to better serve its client base in this significant energy research and development hub.“ABS recognizes that our customer base in the offshore industry demands on-site support with best-in-class services,” says ABS Chairman Christopher J. Wiernicki. “ABS made the strategic decision to provide greater access to our offshore clients by locating ABS’ industry-focused resources in a dedicated facility in one of the world’s most important energy centers. This move reinforces our commitment to support Houston’s leading energy industry.”In addition to class services, ABS’ West Houston facility will offer education and training seminar rooms for local industry to use on demand. The objective is to provide a forum with access to in-house resources that fosters knowledge-based partnerships and information sharing among operators, service providers, academia and regulatory bodies.The facility is scheduled to open in the first quarter 2014.[mappress]Press release, December 9, 2013; Image: ABSlast_img read more

HMAS Success Supports Argo Program

first_imgDuring their transit to the Middle East in November and December 2014, the crew of HMAS Success assisted the Commonwealth Scientific and Industrial Research Organisation with their global Argo program. This innovative project aims to gather up ocean data using robotic floats.Success supported this venture by deploying 8 Argo floats at specified drop points in the Indian Ocean between Western Australia and the Gulf of Oman. The global Argo program relies on over 3000 autonomous drifting sensors from around the world routinely collecting sub-surface observations from the earth’s open ice-free oceans. Around 800 floats need to be deployed each year to maintain coverage and replace those with exhausted batteries.The 1.5 metre profilers drift between 1 to 2 kilometres in depth once deployed.Every 10 days they descend to a depth of 2000 metres and measure water temperature and salinity as they rise back to drifting depth. They repeat this cycle for approximately 4 years, the Australian Department of Defence said.The information collected is transmitted to satellites and relayed to data centres around the world. Argo data compliments other observations collected from ships, moored instruments and earth-observing satellites.Success Officer of the Watch, Sub Lieutenant Rhian Campbell-McBride was involved in coordinating the Argo float drops along the transit. “It is satisfying to think that we are contributing to research for climate change, as that is a significant global concern at the current time,” she said.Australia is a founding contributor to Argo, deploying the first 10 floats in 1999.Since then Australia has deployed over 500 floats on transits similar to this.[mappress mapid=”11265″]last_img read more


first_imgPlanning – Authorisations – Inspectors – Waste disposal The claimant quarry owner (B) applied for judicial review of a decision of an inspector appointed by the defendant secretary of state upholding the refusal of the Environment Agency to grant it a permit to dispose of inert waste at the quarry. Under regulation 10(4)(b) of the Pollution Prevention and Control (England and Wales) Regulations 2000, the Environment Agency was bound to refuse a permit unless planning permission was in force in relation to the use of the site. It was common ground that there was no express conventional grant of planning permission covering the relevant use at the site. However, B’s case was that planning permission existed by virtue of general development orders. B argued that the inspector had failed to deal adequately or at all with its submission that it had the necessary planning permission for the deposit of waste by virtue of historic general development orders. Held: The reasons given by the inspector were inadequate. The issue of the historic general development orders had been fairly before her. Detailed submissions had been made by all parties, but the inspector had not dealt adequately with those submissions. It was not possible for B to know why it lost. However, as this was a reasons challenge, B would succeed only if it could show that it had genuinely been substantially prejudiced by the failure to provide adequate reasons. B was applying for a permit for the whole of the area contained in a waste disposal licence granted in 1983. As there was no express grant of planning permission, it had to show under regulation 10(4)(b) that there was a deemed planning permission for the deposit of waste on the whole of the site. Before 1988, each individual deposit of waste on a site was granted planning permission by the historic general development orders where the superficial area of the deposit was extended so long as the height was not extended above the height of the surrounding land. However, the position changed as a result of the Town and Country Planning General Development Order 1988: the general grant of planning permission enjoyed previously was revoked without any saving provision. Thereafter, any fresh deposit of waste which extended either the superficial area of the deposit or the height of the deposit above that of the adjoining land required an express grant of permission. B therefore had to show that, before 5 December 1988, it had deposited waste on the whole of the site; otherwise there would be no extant permission for those areas which extended the tipping areas beyond the areas that had been tipped on 5 December 1988. The inevitable conclusion from the inspector’s findings, which included a finding that there had been limited tipping after 1983, was that B had not established on the balance of probabilities that it had deposited waste on the whole of the site as at 5 December 1988. Indeed, it was not part of B’s case that it had. In those circumstances, there was no extant permission for the whole of the site. It followed that B could not establish the necessary prejudice for the reasons challenge to succeed. Application refused. John Barrett (instructed by Walker Morris (Leeds)) for the claimant; James Maurici (instructed by in-house solicitor) for the defendant; no appearance or representation for the interested parties.center_img Berry & Marshall (Bolton Wood) Ltd (claimant) v Secretary of State for Environment, Food and Rural Affairs (defendant) and (1) Environment Agency (2) Bradford Metropolitan Borough Council (interested parties): QBD (Admin) (Judge Behrens): 24 September 2010last_img read more